Loving Wellness Now

MTHFR FUT2 Living With Genetic Mutations

Year, 2015

MTHFR, FUT2 & Living with Genetic Defects

By Lisa Rohde, CHC

Trying to remember acronyms is not always easy but when it comes to MTHFR and FUT2, Mother FXXXer and FXXK You Too is quite easy to remember.  When you grasp the concept of what it means to live with MTHFR, FUT2 and other similar genetic defects, you will understand where these terrible language slogans accompanying these acronyms comes from, but first you have to understand Methylation.

Do you have a family history of heart disease or stroke, miscarriages, chronic migraines, depression or irritably bowel syndrome (IBS)?  If yes, than you may be interested in looking in to your family genes.  Genetic testing is readily available and easy to do with a simple blood test, ask your doctor.

First lets understand methylation.  Methylation is a biochemical process that builds neurotransmitters dopamine and corotomin, produces energy, processes hormones, builds immune cells, turns genes on or off, synthesizes DNA, produces protective coatings on our nerves, and detoxifies out cells; this happens in all of our body cells.

One cannot be vibrantly healthy if we are not methylating efficiently.  Symptoms of poor methylation and toxic overload include allergies, fatigue, autism, PMS, heart arrhythmia, and palpitations, IBS, Crone’s, depression, MCS, Alzheimer’s, sleep disorders, and dementia to name a few.  Things that further negatively effect methylation include a deficient diet, genetic mutation, toxic exposure, stress, virus, or infection.

Methylations is the action of an enzyme and enzymes are very fragile and easily damaged by toxins in particular heavy metals.  We are all exposed to toxins in the our air, water, foods we eat, pharmaceuticals, and in general the world today.  Mercury can block methylation and induce a B-12 deficiency.  Proper methylation requires V-B complex, V-B12 and folate.  

What you need to know about the MTHFR genetic defect is that is disrupts the Methylation process reducing your ability to detoxify cells to perhaps only 40%-70%.  This means that you don’t break down toxins or heavy metals well and you could find yourself with heavy metal overload, too much iron, copper, lead, or mercury...

Furthermore, someone with MTHFR gene mutation must avoid all non active or synthetic forms of folate, also known as folic acid, which is found in your average V-B complex and many “enriched” foods.  Look on the food package and if you see the words “enriched” don’t eat it.  Synthetic folate is not metabolized by one with MTHFR gene mutation and instead builds up in the body as a toxic poison.  Too much synthetic folate can cause high homocystein which can lead to coronary heart problems, increased blood pressure and risk of dementia.  The best form of V-B and V-B12 is Methyl B-12 or Methylcobalamin.

FUT2, or fucosyltransferase 2, is a genetic mutation linked towards decreased bifidobacterium, a friendly gut flora, and is associated with Crone’s Disease and IBS.  FUT2 forms sugar polymer known as oligosaccharide which is food for beneficial gut flora.  Approximately 20% of the population has FUT2 gene mutations.  Nutritional strategies and intensive probiotic therapies, along with avoiding toxics and antibiotics will help one manage the FUT2 gene mutation.

The bottom line is living with genetic mutations lowers your immune system and increases your risk of heart disease, cancer, and mental health.  What this means for one with such genetic mutations is that one has to be very careful regarding their nutrition and lifestyle choices.  One has to eat a highly nutritious and cleansing diet, seek probiotic therapy, avoid antibiotics, and be sure to have a healthy lifestyle with plenty of exercise.

How does one end up with a genetic defect, these defective genes are passed down from your parents, your mother, your father, or both parents.  If you discover you have a genetic defect it may be wise for other family members to be tested as well.  Conditions associated with various genetic defects can be managed with nutritious and healthy lifestyle choices.